Your Cholesterol Matters Less Than You Think

The Cholesterol Hypothesis

The cholesterol hypothesis is the prevailing theory on why human beings develop heart disease. It goes something like this; elevated total cholesterol and, especially, elevated LDL cholesterol, is the primary cause of atherosclerosis and cardiovascular disease. Further, replacing saturated fat in the diet with vegetable oils lowers serum cholesterol and, therefore, lowers cardiovascular disease risk. This information is decades old and has become medical dogma. Unfortunately, it’s not true.

Much of this information comes from the Seven Countries Study originating in the 1950s, although data is still analyzed today to glean more knowledge from it. It tied fat consumption to heart disease. The lead author, Ancel Keys, found the more fat a society consumed the higher the rate of heart attacks. It seemed to be very convincing evidence. This observation helped shape health policies for governments and the medical field. In fact, to some degree, it still does today.

Missing or Unpublished Data

There was a problem with it, though. Data showed that there were populations of people who consumed lots of fat but had low heart attack rates. Conversely, there was data showing there were populations of people who consumed very little fat but had high rates of heart attacks. This information was omitted from the study. The study also failed to account for the fact that the people who consumed the most fat were also most likely to consume the most sugar. While nutrition science is notoriously difficult, these seem like variables that shouldn’t have been ignored.

Superimpose the above inconsistencies with interventional studies conducted in the same time period and you’ll quickly see you’ve been misled. Ancel Keys’ study was an observational study. This means he observed a connection between two sets of data. Observational studies cannot prove cause and effect. For example, imagine this headline; “New science has observed a connection between high heel wearing and breast cancer.” Does wearing high heels cause breast cancer? Of course not. It just happens that people who wear high heels (mostly women) also develop the majority of breast cancer. This silly example shows just how easily an observational study can get it wrong.

The gold standard for proving cause and effect is an interventional study where populations are randomized and given either an experimental intervention or are controls, generally receiving a placebo. In dietary trials, placebos are difficult, if not impossible, to give so participants diets are often left unchanged for the control population.

The Sydney Diet Heart Study and the Minnesota Coronary Experiment

Around the same time that Ancel Keys was doing his work, two interventional studies were conducted. One was called the Sydney Diet Heart Study and the other the Minnesota Coronary Experiment. Both of these studies were incompletely published (data was missing) or went completely unpublished for reasons no one really knows. It is likely because they contradicted accepted dogma and scientific journals were hesitant to put their reputations on the line for something they viewed with skepticism. We know about them now because a group of researchers recently uncovered the unpublished data, reanalyzed it with modern methods and found some shocking results. The reanalysis of both studies was published in the British Medical Journal.

In both of these experiments, totaling about 10,000 participants, saturated fat was removed from the diets of the experimental group and replaced with vegetable oils. This is precisely what the American Heart Association says you should do. What did they find? They found that by removing saturated fat, the participants’ cholesterol went down. This is not unexpected. What they didn’t expect to find was that in both studies the low saturated fat group experienced more cardiovascular disease, more coronary heart disease, and an increase in all-cause mortality.

So let’s summarize; Removing saturated fat and replacing it with vegetable oils lowers cholesterol. But lowering cholesterol raised the risk of heart disease? Yes. This puts an enormous, truck-sized hole in the cholesterol hypothesis. In fact, in the Minnesota Coronary Experiment for every 30 points a person’s cholesterol dropped their risk of death increased by 22%.

This information is counter to everything nutrition science says. Three other randomized controlled trials have confirmed the results. Couple this with another very recent study evaluating over 68,000 elderly people which found an inverse relationship in those over 60 between LDL level and mortality, and I think we seriously need to evaluate the cholesterol hypothesis.

The Real Cause of Heart Disease

If cholesterol doesn’t cause heart disease, what does? It’s quite simple actually – endothelial damage. The endothelia are the cells that line your blood vessels. There are things that are known to damage this lining – high blood pressure, inflammation, high blood sugar, smoking, oxidative stress, and aging. These triggers, and pursuant damage, set into motion a cascading set of events that allows your immune system (in the form of white blood cells) to infiltrate the lining of the vessels. Only after they do this do they begin the process of engulfing cholesterol, which eventually leads to arterial plaque formation. Control those triggers and you will never develop heart disease. If you do not control those processes, it doesn’t matter how low your cholesterol is. You will still develop heart disease. I hear you saying, “But how do I control aging?” That is more difficult as we will all age, but living a healthy lifestyle helps with all of those factors, including aging. Plus, aging alone is unlikely to be a significant cause of heart disease.

It’s important to recognize that cholesterol is not your enemy. Sedentary lifestyle, smoking, a diet high in refined food, the excess consumptions of sugar, and poor stress management are much more serious concerns. Lowering cholesterol for the sake of lowering it has no beneficial effect on your heart. As a matter of fact, the research shows it could be downright dangerous for it. So if you’ve been told you have high cholesterol and that lowering it will lower your risk, you might want to consider the information above and seek an alternative.

3 Things That Happen To Your Brain With Leaky Gut

Gut health is essential for overall health. That connection is fairly easy to make. But what about your brain? Can the health of your gut really affect your brain? The answer is a resounding yes! Here are three things that happen to your brain when you have a leaky gut.

1. Depression – the bacteria that naturally exist in our GI tract are mostly beneficial. However, if metabolic byproducts and cell constituents are able to escape the gut they cause a potent inflammatory response. This happens through a “leaky gut.” The resulting response alters levels of inflammatory hormones called cytokines. These cytokines have the ability to communicate with the brain and eventually change neurotransmitter levels. This change in neurotransmission actually begins to rewire the brain leading the changes in how we think and feel. Most often, people begin to feel depressed. 
2. An Inflamed Brain – through the mechanisms just mentioned, not only do your neurotransmitters and thoughts/feelings change, your brain becomes inflamed. This signals the immune cells within the brain, called glial cells, to become very active. This may sound like a good thing, but it’s not. As a result of being activated glial cellsgenerate more inflammation and create oxidative stress. This means the glial cells begin breaking down the brain. This may increase your risk of brain fog, fatigue, depression, anxiety, cognitive decline, and possibly even neurodegenerative disorders like Parkinson’s disease and Alzheimer’s disease.
3. Blood Brain Barrier Breakdown – there is a barrier than exists that separates what is circulating in our blood from our brain. Only things that are beneficial for the brain are supposed to have access to it. The blood brain barrier is an exceptionally important structure. With increased inflammation from a leaky gut and glial activation, the blood brain barrier breaks down. Now toxic byproducts, inflammatory hormones, and other noxious chemicals have free access to the brain. This is a disastrous consequence that interferes with brain function leading to a multitude of symptoms which include depression, brain fog, anxiety, and more. Leaky gut leads to a leaky blood brain barrier!

Gastrointestinal health is essential for brain health. Knowing how to fix the gut can lead to dramatic improvements in how you feel cognitively and emotionally.

For much more information and strategies to improve your gut and brain health join me for a FREE webinar on Tuesday, November 10th at 7:30PM called “The Gut-Brain Connection – Mood, Food, and More!” We’ll explore the amazing connection between gut health and brain health and give you tips and tricks to make both healthy.

Dr. Vreeland is a nationally recognized expert and author in functional medicine and will present information that will be life changing! You don’t want to miss this event!

Click here to register: http://www.anymeeting.com/PIID=EC51D98085463A

4 Unconventional Things You Didn’t Know Were Making You Fat

The human body is a strange and wondrous place. There are many reasons why a person might gain weight. Eating the wrong kind of food, the wrong amount of food, or not enough exercise are well established reasons. However, there are some no-so-common reasons that might play a role as well.

Road Traffic Noise

Exposure to a combination of road traffic, rail, and aircraft noise may pose the greatest risk of acquiring a spare tire — otherwise known as central obesity, and thought to be one of the most harmful types of fat deposition around the body. In a recent study researchers assessed how much road traffic, rail, and aircraft noise 5075 people living in five suburban and rural areas around Stockholm, Sweden, had been exposed to since 1999. The analysis indicated no link between road traffic noise and BMI. But there was an association between road traffic noise and waist size, with a 0.21 cm increase for every additional 5 dB increase in exposure, although this was only significant among women. Similarly, there was a link to waist:hip ratio, with a change of 0.16 for every 5 dB increase in noise exposure to road traffic; this association was stronger in men.

What gives? Noise exposure may be an important physiological stressor and bump up the production of the hormone cortisol, high levels of which are thought to have a role in fat deposition around the middle of the body, researchers suggest. Additionally, noise exposure might disrupt sleep, another known factor to contribute to weight gain.

Too Many Food Choices

A new study in mice by researchers in the Virginia Tech College of Agriculture and Life Sciences and the Edward Via College of Osteopathic Medicine has shown that the environment in which a child lives may be an equal if not stronger force in determining obesity than their mother’s diet. Researchers found that having too many food choices increases the obesity problem. In fact, researchers found that having a choice of a high-fat and low-fat diet does not help — offspring in this situation tended to eat even more. Their findings were recently released in the journal Endocrinology. “We like variety,” said Deborah Good, an author of the paper and an associate professor of human nutrition, foods, and exercise at Virginia Tech. “But when there is a choice, we eat more than when there is not any variety.” Moral of the story? Simple is better for our waistlines.

The Inability To Stay Warm

A new study suggests that a biological inability to create sufficient core body heat could be linked to the obesity epidemic. The study found that obesity is associated with a significant reduction of body core temperature during daytime hours. Journal Editor Francesco Portaluppi explains that the reduced ability of obese people to spend energy as heat compared to lean individuals could result in long term weight gain (about 2 kg (4.5 lb.)) per year, depending on the lifestyle. “Since body core temperature represents a marker of energy expenditure, results from this study suggest that a diurnal thermogenic handicap can play a crucial role in favoring weight gain in obese subjects,” said article co-author Pietro Cortelli, MD, Ph.D. The fix? Generate more body heat. And how does one do that? Exercise of course!

Environmental Pollution

A team of Spanish scientists, which includes several researchers from the University of Granada, has confirmed that there is a relation between the levels of certain environmental pollutants that a person accumulates in his or her body and their level of obesity. Subjects with more pollutants in their bodies tend to have higher levels of cholesterol and triglycerides, which are important risk factors for cardiovascular disease. The research has analyzed the levels of pollutants accumulated in adipose tissue (fat) in nearly 300 men and women, who were attended in the surgery services of two hospitals in the province of Granada (Spain). The substances analyzed, known as persistent organic pollutants (POPs), can remain in the environment for years, even decades, without degrading.

“Humans are exposed to POPs mainly through diet. Besides, POPs accumulate gradually in body fat, and this is the reason why the median levels in our study give us an idea of an individual’s accumulated exposition over a number of years,” says Juan Pedro Arrebola, the main author of the article. There is evidence that human exposure to certain chemical substances called “obesogenic” could favor the growth and proliferation of adipocytes (fat cells), and provoke therefore an increase in body fat.

Do your best to avoid exposing yourself unnecessarily to chemicals that might be problematic. Perhaps the most powerful way to do this is avoid processed food which is loaded with these chemicals from their own packaging.

How to develop healthy eating habits in a child: Start early and eat your vegetables

A healthy diet promotes success in life — better concentration and alertness, better physical health that translates into good mental and emotional health.

But even the best intentioned parents can expect food fights with their children, said Tanda Kidd, associate professor of human nutrition and extension specialist at Kansas State University. Developing good eating habits in your children is worth the effort, she said.

Good eating habits also are a front-line defense against obesity, a scourge of the nation that happens when a child eats many more calories than he or she uses up.

Nearly 1 in 4 children ages 2 to 5 is overweight or obese, said Paula Peters. An obese child is at risk for developing diabetes, high blood pressure, asthma and sleep apnea. Peters is an associate professor of human nutrition and assistant extension director for family and consumer sciences at Kansas State University.

“No parent wants her child to be sick. No parent wants her child to feel like an outsider in social situations, or be teased or bullied because of her weight,” Kidd said.

Peters and Kidd both conduct research in the area of childhood obesity prevention.

A primary key to teaching a child to make healthy food choices, Peters said, is to start early.

“Give the child a wide variety of healthy food options and let her choose which and how much to eat. A child may start by eating nothing or eating too much, but she has an innate ability to know when she’s hungry and when she’s full.”

A child learns about new foods at a time when she is exploring the world around her. And she learns to make decisions for herself.

Make the selection nutrient dense — not calorie dense. That means fruits and vegetables, not cookies for snacks. A glass of soda and a glass of 100 percent juice may have the same number of calories, but a juice is a healthier choice because it does not contain added sugars, said Kidd, a registered dietitian.

Soda and other sugar-sweetened drinks have empty calories, meaning they are “empty” of nutritional value.

According to the Centers for Disease Control, empty calories from foods high in added sugars, such as ice cream, cookies, candy, fruit drinks and some breakfast cereals and solid fats such as donuts, pastries, hot dogs, sausages, bacon and regular ground beef, contribute to 40 percent of daily calories for children and adolescents ages 2 to 18 years.

Kidd and Peters offer other suggestions:

• Do not use food as a reward for good behavior or other achievements. Kidd suggested other awards like reading a book together or playing a child’s favorite game.

• Eat your veggies, Dad. A child learns food habits — what to eat, how much to eat, when to eat, where to eat — from parents.

• Eat with your children so they can see you making good food choices.

• Be aware of what a child is eating away from home. Peters said that more than 25 percent of children ages 2 to 4 are in day care 20 to 40 hours a week. Check out meals and snacks offered to your child.

• Limit screen time — television — that encourages “mindless” eating.

• Avoid putting a child on a diet, even if he or she is slightly overweight. “That sets up the child for issues such as eating disorders later in life,” Kidd said. Instead, offer healthier food options and increase physical activity.

Kidd and Peters also encourage parents to teach their children about healthy food choices in other ways:

• Planning and taking a trip to the grocery store gives a child ownership in food choices. Reading labels and comparing costs offer other lessons.

• Plant a garden. Peters said a child is more likely to eat vegetables he or she helped grow and harvest.

• Cook together. During special time with Mom or Dad in the kitchen the child will learn more than cooking skills.

Kidd and Peters are concerned about both food deserts and food swamps. The former defines area where fresh foods are hard to get, perhaps because grocery stores are far from the family home.

Food swamps describes areas that are so crowded with fast food options that making healthy eating choices is more challenging.

They also stress the vital role that physical activity plays in childhood health. Although there is no specific recommendation for kids ages 2-5 years old, parents should offer opportunities several times a day for active play. However, kids 6 and over are encouraged to be physically active at least 60 minutes each day, Kidd said.

“Parenting styles and family characteristics affect what a child eats, of course,” Peters said. “So do community, demographic and societal characteristics such as school physical education programs, access to recreational facilities, school lunch programs and neighborhood safety.

“Weight gain is an indicator of an unhealthy society,” she said. “We have to focus on ways to be healthier.”

Week of the Young Children, sponsored by the National Association for the Education of Young Children April 12-18, focuses on the foundation for a child’s success in school and later life.

via How to develop healthy eating habits in a child: Start early and eat your vegetables — ScienceDaily.

Dr. Court’s Comments:

I agree with everything written above with one exception. I do not believe fruit juice should be a regular part of a child’s diet. On occasion, it’s fine. However, the vast majority of time, water should be the choice. Parents often are concerned that their children are somehow “missing” something if they aren’t given juice or sweet snacks. They are missing something; they’re missing the opportunity for cavities. They’re missing the increased risk of being overweight or obese. They’re missing out on poorer brain function. They’re missing out on learning healthy habits.

In all seriousness though, parents are legitimately concerned about depriving their children of delicious treats. However, this is purely the parents’ perspective, not the child’s. If the parent believes they would miss those treats themselves (most likely because of their own upbringing and food choices), of course they’re going to believe their children would miss them too. Here’s the caveat though. Children only know what you teach them. They won’t miss out on anything if they’re taught to love the healthy food. They’ll feel just as fulfilled and loved with the good food as they would feel with the unhealthy food.

This is not to suggest treats should never be given. They must, however, be just that – treats. Making a regular habit of bad food choices sets up a child for a lifetime of health issues.

Omega-3: Intervention for childhood behavioral problems? — ScienceDaily

At the forefront of a field known as “neurocriminology,” Adrian Raine of the University of Pennsylvania has long studied the interplay between biology and environment when it comes to antisocial and criminal behavior. With strong physiological evidence that disruption to the emotion-regulating parts of the brain can manifest in violent outbursts, impulsive decision-making and other behavioral traits associated with crime, much of Raine’s research involves looking at biological interventions that can potentially ward off these behavioral outcomes.

A new study by Raine now suggests that omega-3, a fatty acid commonly found in fish oil, may have long-term neurodevelopmental effects that ultimately reduce antisocial and aggressive behavior problems in children.

He is a Penn Integrates Knowledge Professor with appointments in the School of Arts & Sciences and the Perelman School of Medicine.

Along with Raine, the study featured Jill Portnoy a graduate student in the Department of Criminology, and Jianghong Liu, an associate professor in the Penn School of Nursing. They collaborated with Tashneem Mahoomed of Mauritius’ Joint Child Health Project and Joseph Hibbeln of the National Institute on Alcohol Abuse and Alcoholism.

It was published in the Journal of Child Psychology and Psychiatry.

When Raine was a graduate student, he, his advisor and colleagues conducted a longitudinal study of children in the small island nation of Mauritius. The researchers tracked the development of children who had participated in an enrichment program as 3-year-olds and also the development of children who had not participated. This enrichment program had additional cognitive stimulation, physical exercise and nutritional enrichment. At 11 years, the participants showed a marked improvement in brain function as measured by EEG, as compared to the non participants. At 23, they showed a 34 percent reduction in criminal behavior.

Raine and his colleagues were interested in teasing apart the mechanisms behind this improvement. Other studies suggested the nutritional component was worth a closer look.

“We saw children who had poor nutritional status at age 3 were more antisocial and aggressive at 8, 11 and 17,” Raine said. “That made us look back at the intervention and see what stood out about the nutritional component. Part of the enrichment was that the children receiving an extra two and a half portions of fish a week.”

Other research at the time was beginning to show that omega-3 is critical to brain development and function.

“Omega-3 regulates neurotransmitters, enhances the life of a neuron and increases dendritic branching, but our bodies do not produce it. We can only get it from the environment,” Raine said.

Research on the neuroanatomy of violent criminals suggested this might be a place to intervene. Other brain-imaging researchers have shown that omega-3 supplementation increases the function of the dorsolateral prefrontal cortex, a region Raine found to have higher rates of damage or dysfunction in criminal offenders.

Raine’s new study featured a randomized controlled trial where children would receive regular omega-3 supplements in the form of a juice drink. One hundred children, aged 8 to 16, would each receive a drink containing a gram of omega-3 once a day for six months, matched with 100 children who received the same drink without the supplement. The children and parents in both groups took a series of personality assessments and questionnaires at the start.

After six months, the researchers administered a simple blood test to see if the children in the experimental group had higher levels of omega-3 than those in the controls. They also had both parents and children take the personality assessments. Six months after that, the researchers had parents and children take the assessment again to see if there were any lasting effects from the supplements.

The assessments had parents rate their children on “externalizing” aggressive and antisocial behavior, such as getting into fights or lying, as well as “internalizing” behavior, such as depression, anxiety and withdrawal. Children were also asked to rate themselves on these traits.

While the children’s self-reports remained flat for both groups, the average rate of antisocial and aggressive behavior as described by the parents dropped in both groups by the six-month point. Critically, however, those rates returned to the baseline for the control group but remained lowered in the experimental group, at the 12-month point.

“Compared to the baseline at zero months,” Raine said, “both groups show improvement in both the externalizing and internalizing behavior problems after six months. That’s the placebo effect.

“But what was particularly interesting was what was happening at 12 months. The control group returned to the baseline while the omega-3 group continued to go down. In the end, we saw a 42 percent reduction in scores on externalizing behavior and 62 percent reduction in internalizing behavior.”

At both the six- and 12-month check-ins, parents also answered questionnaires about their own behavioral traits. Surprisingly, parents also showed an improvement in their antisocial and aggressive behavior. This could be explained by the parents taking some of their child’s supplement, or simply because of a positive response to their child’s own behavioral improvement.

The researchers caution that this is still preliminary work in uncovering the role nutrition plays in the link between brain development and antisocial behavior. The changes seen in the one-year period of the experiment may not last, and the results may not be generalizable outside the unique context of Mauritius.

Beyond these caveats, however, there is reason to further examine omega-3’s role as a potential early intervention for antisocial behavior.

“As a protective factor for reducing behavior problems in children,” Liu said, “nutrition is a promising option; it is relatively inexpensive and can be easy to manage.”

Follow-up studies will include longer-term surveillance of children’s behavioral traits and will investigate why their self-reports did not match the parental reports.

via Omega-3: Intervention for childhood behavioral problems? — ScienceDaily.

Dr. Court’s Comments:

Fortunately, science is finally studying and understanding that nutrition is a major factor in brain development. This development appears to have a critical window and if this window is missed, it increases the risk of adverse outcomes. As with many other aspects of our health, it is the combination of our unique genetics with our environment. It’s important to provide the best environment possible to give a child the best chance at a healthy life. Modern American diets are notoriously low in omega-3s. According to recent a recent study, the average American consumes between 100-149mg/day of omega-3s from seafood. This is lower than the world average of 163mg/day. All this despite having relatively easy access to foods that contain omega-3s. Don’t like seafood? Consider increasing your consumption of grass-fed products which tend to be high in omega-3s. Also consider taking a fish oil supplement.

Eight nutrients to protect the brain

Brain health is the second most important component in maintaining a healthy lifestyle according to a 2014 AARP study. As people age they can experience a range of cognitive issues from decreased critical thinking to dementia and Alzheimer’s disease. In the March issue of Food Technology published by the Institute of Food Technologists (IFT), contributing editor Linda Milo Ohr writes about eight nutrients that may help keep your brain in good shape.

1. Cocoa Flavanols: Cocoa flavanols have been linked to improved circulation and heart health, and preliminary research shows a possible connection to memory improvement as well. A study showed cocoa flavanols may improve the function of a specific part of the brain called the dentate gyrus, which is associated with age-related memory (Brickman, 2014).

2. Omega-3 Fatty Acids: Omega-3 fatty acids have long been shown to contribute to good heart health are now playing a role in cognitive health as well. A study on mice found that omega-3 polyunsaturated fatty acid supplementation appeared to result in better object recognition memory, spatial and localizatory memory (memories that can be consciously recalled such as facts and knowledge), and adverse response retention (Cutuli, 2014). Foods rich in omega-3s include salmon, flaxseed oil, and chia seeds.

3. Phosphatidylserine and Phosphatidic Acid: Two pilot studies showed that a combination of phosphatidylserine and phosphatidic acid can help benefit memory, mood, and cognitive function in the elderly (Lonza, 2014).

4. Walnuts: A diet supplemented with walnuts may have a beneficial effect in reducing the risk, delaying the onset, or slowing the progression of Alzheimer’s disease in mice (Muthaiyah, 2014).

5. Citicoline: Citicoline is a natural substance found in the body’s cells and helps in the development of brain tissue, which helps regulate memory and cognitive function, enhances communication between neurons, and protects neural structures from free radical damage. Clinical trials have shown citicoline supplements may help maintain normal cognitive function with aging and protect the brain from free radical damage. (Kyowa Hakko USA).

6. Choline: Choline, which is associated with liver health and women’s health, also helps with the communication systems for cells within the brain and the rest of the body. Choline may also support the brain during aging and help prevent changes in brain chemistry that result in cognitive decline and failure. A major source of choline in the diet are eggs.

7. Magnesium: Magnesium supplements are often recommended for those who experienced serious concussions. Magnesium-rich foods include avocado, soy beans, bananas and dark chocolate.

8. Blueberries: Blueberries are known to have antioxidant and anti-inflammatory activity because they boast a high concentration of anthocyanins, a flavonoid that enhances the health-promoting quality of foods. Moderate blueberry consumption could offer neurocognitive benefits such as increased neural signaling in the brain centers.

via Eight nutrients to protect the aging brain — ScienceDaily.

Reference: Institute of Food Technologists (IFT). “Eight nutrients to protect the aging brain.” ScienceDaily. ScienceDaily, 15 April 2015. <www.sciencedaily.com/releases/2015/04/150415203340.htm>.

Dr. Court’s Comments:

This is a great list. I’d encourage people to consider adding some, if not all, of these to their diet. However, these alone will not be 100% protective. To get much closer to that elusive 100% mark, exercise must be included. The benefits of exercise on the brain are numerous. Exercise is inherently anti-inflammatory. It improves fuel delivery as well as waste removal in the brain. It increases neural feedback which preserves synaptic connections. Remember this fact; 90% of the information coming into the brain on a daily basis is from proprioception. That is, 90% of the information is from our muscles and our joints. A sedentary lifestyle reduces this flow of information, reducing the survivability of neurons in the central nervous system. Exercise also keeps the heart healthy, and a healthy heart means a healthy brain.

9 Signs You Have A Leaky Gut

The gut is the gateway to health. If your gut is healthy, chances are that you’re in good health. However, there’s a condition called leaky gut that can lead to a host of health problems.

What is a leaky gut?

The gut is naturally permeable to very small molecules in order to absorb these vital nutrients. In fact, regulating intestinal permeability is one of the basic functions of the cells that line the intestinal wall. In sensitive people, gluten can cause the gut cells to release zonulin, a protein that can break apart tight junctions in the intestinal lining. Other factors — such as infections, toxins, stress and age — can also cause these tight junctions to break apart.

Once these tight junctions get broken apart, you have a leaky gut. When your gut is leaky, things like toxins, microbes, undigested food particles, and more can escape from your intestines and travel throughout your body via your bloodstream. Your immune system marks these “foreign invaders” as pathogens and attacks them. The immune response to these invaders can appear in the form of any of the nine signs you have a leaky gut, which are listed below.

What causes leaky gut?

The main culprits are foods, infections, and toxins. Gluten is the number one cause of leaky gut. Other inflammatory foods like dairy or toxic foods, such sugar and excessive alcohol, are suspected as well. The most common infectious causes are candida overgrowth, intestinal parasites, and small intestine bacterial overgrowth (SIBO). Toxins come in the form of medications, like Motrin, Advil, steroids, antibiotics, and acid-reducing drugs, and environmental toxins like mercury, pesticides and BPA from plastics. Stress and age also contribute to a leaky gut.

If you suffer from any of the following conditions, it’s likely that you have a leaky gut:

9 Signs You Have a Leaky Gut

1. Digestive issues such as gas, bloating, diarrhea or irritable bowel syndrome (IBS).

2. Seasonal allergies or asthma.

3. Hormonal imbalances such as PMS or PCOS.

4. Diagnosis of an autoimmune disease such as rheumatoid arthritis, Hashimoto’s thyroiditis, lupus, psoriasis, or celiac disease.

5. Diagnosis of chronic fatigue or fibromyalgia.

6. Mood and mind issues such as depression, anxiety, ADD or ADHD.

7. Skin issues such as acne, rosacea, or eczema.

8. Diagnosis of candida overgrowth.

9. Food allergies or food intolerances.

How do you heal a leaky gut?

1. Remove.

Remove the bad. The goal is to get rid of things that negatively affect the environment of the GI tract, such as inflammatory and toxic foods, and intestinal infections.

2. Replace.

Replace the good. Add back the essential ingredients for proper digestion and absorption, such as digestive enzymes, hydrochloric acid and bile acids.

3. Reinoculate.

It’s critical to restore beneficial bacteria to reestablish a healthy balance of good bacteria.

4. Repair.

It’s essential to provide the nutrients necessary to help the gut repair itself. One of my favorite supplements is L-glutamine, an amino acid that helps to rejuvenate the lining of the gut wall.

If you still have symptoms after following the above recommendations, I would recommend finding a Functional Medicine physician in your area to work with you and to order a comprehensive stool test.

via 9 Signs You Have A Leaky Gut.

Dr. Court’s Comments:

Leaky gut was once considered quackery. Today, an abundance of research supports that it does exist and that it plays a major role in many diseases. Much of what we do in our day to day lives contributes to the development of leaky gut. If you know what these factors are, they are easily avoided and optimal health is easily achieved.

If you’d like more detail, including in depth examination of the techniques you can use to heal leaky gut, watch my webinar here:

Ibuprofen Kills Thousands Each Year. Here are 10 Natural Alternatives

A recent Reuters’ article opened with the following stunning sentence:

“Long-term high-dose use of painkillers such as ibuprofen or diclofenac is ‘equally hazardous’ in terms of heart attack risk as use of the drug Vioxx, which was withdrawn due to its potential dangers, researchers said.”

The 2004 Vioxx recall, as you may remember, was spurred by the nearly 30,000 excess cases of heart attacks and sudden cardiac deaths caused by the drug between 1999-2003. Despite the fact that scientific research had accumulated as early as 2000 linking Vioxx to increased heart attacks and strokes, the drug’s manufacturer Merck, and the FDA, remained silent as the death toll steadily increased.

The Reuters report focused on new research published in Lancet indicating the risk of heart attack increases as much as a third and the risk of heart failure doubles among heavier users of NSAID drugs.

INFLAMED: Our Default Bodily State

Why are so many folks taking NSAID drugs like ibuprofen anyway?

Pain and unhealthy levels of inflammation are fast becoming default bodily states in the industrialized world. While in most cases we can adjust the underlying pro-inflammatory conditions by altering our diet, and reducing stress and environmental chemical exposures, these approaches take time, discipline and energy, and sometimes we just want the pain to stop now. In those often compulsive moments we find ourselves popping an over-the-counter pill to kill the pain.

The problem with this approach is that, if we do it often enough, we may kill ourselves along with the pain…

Ibuprofen really is a perfect example of this. As mentioned above, this petrochemical-derivative has been linked to significantly increased risk of heart attack and increased cardiac and all-cause mortality (when combined with aspirin), with over two dozen serious adverse health effects, including:

• Anemia[1]
• DNA Damage[2]
• Hearing Loss[3]
• Hypertension[4]
• Influenza Mortality[5]
• Miscarriage[6]

Ibuprofen is, in fact, not unique in elevating cardiovascular disease risk and/or mortality. The entire category of non-steroidal anti-inflammatory drugs (NSAIDs) appears to have this under-recognized dark side; cardiovascular disease and cardiac mortality score highest on the list of over 100 unintended adverse health effects associated with their use. See also our analysis of the rarely acknowledged dark side to aspirin: The Evidence Against Aspirin And For Natural Alternatives.

So, what does one do? Pain is pain. Whether it happens to you, or you witness it in another (which can be worse), finding relief is a top priority.

Research on Natural Alternatives To Ibuprofen

Here is some evidence-based research on alternatives to ibuprofen, sourced from the National Library of Medicine:

1. Ginger – A 2009 study found that ginger capsules (250 mg, four times daily) were as effective as the drugs mefenamic acid and ibuprofen for relieving pain in women associated with their menstrual cycle (primary dysmenorrhea). [7]
2. Topical Arnica – A 2007 human study found that topical treatment with arnica was as effective as ibuprofen for hand osteoarthritis, but with lower incidence of side effects.[8]
3. Combination: Astaxanthin, Ginkgo biloba and Vitamin C – A 2011 animal study found this combination to be equal to or better than ibuprofen for reducing asthma-associated respiratory inflammation.[9]
4. Chinese Skullcap (baicalin) – A 2003 animal study found that a compound in Chinese skullcap known as baicalin was equipotent to ibuprofen in reducing pain.[10]
5. Omega-3 fatty acids: A 2006 human study found that omega-3 fatty acids (between 1200-2400 mg daily) were as effective as ibuprofen in reducing arthritis pain, but with the added benefit of having less side effects.[11]
6. Panax Ginseng – A 2008 animal study found that panax ginseng had analgesic and anti-inflammatory activity similar to ibuprofen, indicating its possible anti-rheumatoid arthritis properties.[12]
7. St. John’s Wort – A 2004 animal study found that St. John’s wort was twice as effective as ibuprofen as a pain-killer.[13]
8. Anthrocyanins from Sweet Cherries & Raspberries – A 2001 study cell study found that anthrocyanins extracted from raspberries and sweet cherries were as effective as ibuprofen and naproxen at suppressing the inflammation-associated enzyme known as cyclooxygenase-1 and 2.[14]
9. Holy Basil – A 2000 study found that holy basil contains compounds with anti-inflammatory activity comparable to ibuprofen, naproxen and aspirin.[15]
10. Olive Oil (oleocanthal) – a compound found within olive oil known as oleocanthal has been shown to have anti-inflammatory properties similar to ibuprofen.[16]

[1] Direct cytotoxicity of non-steroidal anti-inflammatory drugs in acidic media: model study on human erythrocytes with DIDS-inhibited anion exchanger. Pharmazie. 2002 Dec;57(12):848-51. PMID: 12561250

[2] Genotoxicity of ibuprofen in mouse bone marrow cells in vivo. Drug Chem Toxicol. 2012 Jan 27. Epub 2012 Jan 27. PMID: 22283434

[3] Analgesic use and the risk of hearing loss in men. Am J Med. 2010 Mar;123(3):231-7. PMID: 20193831

[4] Effect on blood pressure of lumiracoxib versus ibuprofen in patients with osteoarthritis and controlled hypertension: a randomized trial. J Hypertens. 2008 Aug;26(8):1695-702. PMID: 18622250

[5] The effect on mortality of antipyretics in the treatment of influenza infection: systematic review and meta-analysis. J R Soc Med. 2010 Oct;103(10):403-11. PMID: 20929891

[6]  Taking non-aspirin NSAIDs in early pregnancy doubles risk of miscarriage, study shows. BMJ. 2011 ;343:d5769. Epub 2011 Sep 9. PMID: 21908536

[7] Comparison of effects of ginger, mefenamic acid, and ibuprofen on pain in women with primary dysmenorrhea. J Altern Complement Med. 2009 Feb 13. PMID: 19216660

[8] Choosing between NSAID and arnica for topical treatment of hand osteoarthritis in a randomised, double-blind study. Rheumatol Int. 2007 Apr;27(6):585-91. Epub 2007 Feb 22. PMID: 17318618

[9] Summative interaction between astaxanthin, Ginkgo biloba extract (EGb761) and vitamin C in suppression of respiratory inflammation: a comparison with ibuprofen. Phytother Res. 2011 Jan;25(1):128-36. PMID: 20632299

[10] The antiinflammatory and analgesic effects of baicalin in carrageenan-evoked thermal hyperalgesia. Anesth Analg. 2003 Dec;97(6):1724-9. PMID: 14633550

[11] Omega-3 fatty acids (fish oil) as an anti-inflammatory: an alternative to nonsteroidal anti-inflammatory drugs for discogenic pain. Surg Neurol. 2006 Apr;65(4):326-31. PMID: 16531187

[12] Potential analgesic and anti-inflammatory activities of Panax ginseng head butanolic fraction in animals. Food Chem Toxicol. 2008 Dec;46(12):3749-52. Epub 2008 Oct 1. PMID: 18930781

[13] Antinociceptive activity of methanolic extracts of St. John’s Wort (Hypericum perforatum) preparation. Pak J Pharm Sci. 2004 Jul;17(2):13-9. PMID: 16414593

[14] Cyclooxygenase inhibitory and antioxidant cyanidin glycosides in cherries and berries. Phytomedicine. 2001 Sep;8(5):362-9. PMID: 11695879

[15] Antioxidant and cyclooxygenase inhibitory phenolic compounds from Ocimum sanctum Linn. Phytomedicine. 2000 Mar;7(1):7-13. PMID: 10782484

[16] Molecular mechanisms of inflammation. Anti-inflammatory benefits of virgin olive oil and the phenolic compound oleocanthal. Curr Pharm Des. 2011 ;17(8):754-68. PMID: 21443487.

via Ibuprofen Kills Thousands Each Year, So What Is The Alternative?.

Dr. Court’s Comments:

When approaching pain, it’s best to always address the source of the pain. If it’s structural, a chiropractor is a good option. If it’s metabolic, such as an autoimmune disease, then a doctor trained in functional medicine will be best. They will likely use some of the things listed above to provide relief in addition to functional testing designed to treat the cause of your symptoms, not simply cover them up with medication. Dietary changes are almost always needed. The American diet is pro-inflammatory with high levels of omega-6 fatty acids. These omega-6s feed the inflammatory pathways, allowing people to over produce the pain causing molecules. Once this is addressed, people often feel much better. Remember, just about every chemical we make in our bodies, good or bad, is heavily dependent on dietary factors. If you correct those dietary factors, you correct the dysfunction.

Are you eating your way to a hormonal imbalance? 50 foods to avoid.

PROPYL PARABEN

Are you eating an endocrine disruptor?

The pastry you’re thinking about buying may contain the preservative propyl paraben, linked to disruptions in hormone signaling.

According to ingredient data obtained by EWG’s Food Scores: Rate Your Plate, an online database and app that helps consumers eat healthier, propyl paraben is in 49 widely-available processed foods, including Sara Lee cinnamon rolls, Weight Watchers cakes and La Banderita Corn Tortillas.

Last year, EWG turned the spotlight on propyl paraben in its Dirty Dozen Guide To Food Additives because the federal Food and Drug Administration has listed its use in food as “Generally Recognized As Safe.” Despite mounting evidence that propyl paraben disrupts the endocrine system, the FDA has failed to take action to eliminate its use in food or reassess its safety.

In 2002 researchers at the Tokyo Metropolitan Institute of Public Health discovered that propyl paraben decreased sperm counts in young rats at and below the concentrations which the U.S. Food and Drug Administration considers safe for human consumption in food (Oishi 2002; 21CFR184.1670).

Other researchers have confirmed propyl paraben’s effects on the endocrine system. It acts as a synthetic estrogenic compound and can alter hormone signaling and gene expression (Routledge 1998; Terasaka 2006; Vo 2011; Wróbel 2014). A recent study by researchers at the Harvard School of Public Health suggested that exposure to propyl paraben might be associated with diminished fertility (Smith 2013).

Proper endocrine signaling is particularly important during critical windows of development—while in the womb and during childhood and adolescence. Chemicals that disrupt hormone signaling can lead to adverse effects on development, reproduction, and the neurological and immune systems.

Citing the study by the researchers in Tokyo, the European Food Safety Authority issued an advisory in 2004 that the presumed safe exposure level for propyl paraben in food was no longer valid because it affected sex hormones and the male reproductive organs in young rats (EFSA 2004). Based on that advice, in 2006, regulators removed propyl paraben from the list of food additives authorized for use in the European Union.

Propyl paraben is starting to disappear from some cosmetics, so it is a wonder that it is still allowed in food. If you browse the personal care product aisles in any drug store, you are likely to see labels advertising that certain body washes, lotions, and other items are “paraben free”. Under pressure from EWG and other health advocates, in August 2012 Johnson & Johnson voluntarily pledged to remove this and other members of the paraben family from all its baby products. Brands such as Alba, Origins and Burt’s Bees don’t use parabens at all.

Yet Americans are still widely exposed to this chemical. In 2010 research led by Antonia Calafat, Ph.D., a respected chemist at the federal Centers for Disease Control and Prevention, reported that 92.7 percent of Americans tested had propyl paraben in their urine (Calafat 2010).

via Propyl Paraben | EWG.

50 Foods Containing Propyl Paraben

• Amport Foods Chocolate & Nut Trail Mix
• Archer Farms Gourmet Dessert Cookies
• Arizona Snack Company Canyon Runner II Trail
• Arizona Snack Company Sweet Energy Trail
• Cafe Valley Apple Spice Mini Muffins Apple Spice
• Cafe Valley Banana Nut Mini Muffins
• Cafe Valley Blueberry Mini Muffins
• Cafe Valley Cake Pumpkin Cream Cheese
• Cafe Valley Chocolate Chips Mini Muffins
• Cafe Valley Corn Mini Muffins
• Cafe Valley Lemon Poppyseed Mini Muffins
• Cafe Valley Orange Cranberry Mini Muffins
• Cafe Valley Pumpkin Chocolate Chip Mini Muffins
• Creative Occasions Old Fashioned Carrot Cream Cheese Cake
• Elizabeth’s Naturals Psychedelic Sunday Mix
• Emerald Breakfast On The Go Peanut Butter Chocolate Banana Nut & Granola Mix
• Energy Club Fancy Mojo Mix
• Energy Club Nuts N Chocolate Blend
• Entenmann’s Coconut Crunch Donuts
• Essential Everyday Classic Trail Mix
• Island Snacks Fancy Chocolate Mix
• La Banderita White Corn Tortillas
• La Banderita Yellow Corn Tortillas
• Little Debbie Pecan Spinwheels
• Newton’s Naturals Get The Munchies Trail Mix
• Nuevo Leon Tortillas
• Oh Yeah! Candies Chocolate Caramel
• Ole Mexican Foods Corn Tortillas
• Patissa Pumpkin Pie Cream Puffs
• Premium Orchard Rainbow Trail Mix
• Private Selection Strawberry Rhubarb Pie
• Quality Club Deluxe Moxxi Mix
• Roundy’s Cranberry Trail Mix
• Roundy’s Pak O Snax
• Sara Lee Cinnamon Rolls
• Sara Lee Honey Glazed Buns
• Setton Farms Hiker’s Trail Mix
• Superior Chocolate Nut Trail Mix
• Superior Mini Chocolate Eclairs
• Sweet P’s Bake Shop Black & White Cookies
• Tropical Corn Tortillas, Traditional Style
• Turano Brat & Sausage Rolls
• Weight Watchers Carrot Crème Cake
• Weight Watchers Chocolate Crème Cake
• Weight Watchers Golden Sponge Cake
• Weight Watchers Lemon Creme Cake
• Weight Watchers Red Velvet Creme Cake
• Weis Cross’n Country
• Weis Milk Chocolate Candies

References:

Calafat AM, Ye X, Wong LY, Bishop AM, Needham LL. 2010. Urinary concentrations of four parabens in the U.S. population: NHANES 2005-2006. Environ Health Perspect. 118(5):679-85.

21CFR184.1670. Available: http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=184.1670 [Accessed February 7, 2015]

EFSA. 2004. Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to para hydroxybenzoates (E 214-219). EFSA Journal. 83, 1-26.

Oishi S. Effects of propyl paraben on the male reproductive system. Food Chem Toxicol. 2002 Dec;40(12):1807-13.

Routledge EJ, Parker J, Odum J, Ashby J, Sumpter JP. 1998. Some alkyl hydroxy benzoate preservatives (parabens) are estrogenic. Toxicol Appl Pharmacol. 153(1):12-9.

Smith KW, Souter I, Dimitriadis I, Ehrlich S, Williams PL, Calafat AM, Hauser R. 2013. Urinary paraben concentrations and ovarian aging among women from a fertility center. Environ Health Perspect. 121(11-12):1299-305.

Terasaka S, Inoue A, Tanji M, Kiyama R. 2006. Expression profiling of estrogen-responsive genes in breast cancer cells treated with alkylphenols, chlorinated phenols, parabens, or bis- and benzoylphenols for evaluation of estrogenic activity. Toxicol Lett. 163(2):130-41. Epub 2005 Nov 8.

Vo TT, Jung EM, Choi KC, Yu FH, Jeung EB. 2011. Estrogen receptor α is involved in the induction of Calbindin-D(9k) and progesterone receptor by parabens in GH3 cells: a biomarker gene for screening xenoestrogens. Steroids. 76(7):675-81.

Wróbel AM, Gregoraszczuk EL. 2014. Actions of methyl-, propyl- and butylparaben on estrogen receptor-α and -β and the progesterone receptor in MCF-7 cancer cells and non-cancerous MCF-10A cells. Toxicol Lett. 230(3):375-381

Dr. Court’s Comments:

Endocrine disruptors like parabens and others such as BPA, PFOA, phthalates,  and PCBs are potent chemicals that surround us ubiquitously. Their ability to disrupt our hormonal system has lead to changes in how our bodies function. BPA was originally created as a synthetic estrogen, albeit a weak one. However, because we are exposed to it all the time, those weak estrogenic effects are magnified. BPA, PFOA, phthalates and PCBs are classified as obesogens. That means they cause weight gain. They do this by increasing the number of fat cells we have and increasing our ability to store fat. More fat cells storing more fat means we are increasingly overweight. Avoidance of these chemicals is probably impossible, however, do your best to minimize exposure. First and foremost, avoid processed foods. They are loaded with these chemicals. Secondly, buy products that specify ‘BPA free’ or ‘phthalate free.’ Last, but not least, exercise regularly to assist your body in detoxifying you system.

Exercise largely absent from US medical school curriculum, study shows

Exercise may play a critical role in maintaining good health, but fewer than half of the physicians trained in the United States in 2013 received formal education or training on the subject, according to new research from Oregon State University.

A review of medical school curriculums showed that a majority of U.S. institutions did not offer any courses on physical activity, and when the courses were offered, they were rarely required, said Brad Cardinal, a professor of exercise and sport science in OSU’s College of Public Health and Human Sciences. That could leave doctors ill-prepared to assist patients who could benefit from exercise, said Cardinal, the study’s lead author.

“There are immense medical benefits to exercise; it can help as much as medicine to address some health concerns,” said Cardinal, who is a national expert on the benefits of physical activity. “Because exercise has medicinal as well as other benefits, I was surprised that medical schools didn’t spend more time on it.”

An article on the findings has been accepted for publication in an upcoming issue of the Journal of Physical Activity and Health. Co-authors are Eugene A. Park and MooSong Kim of OSU, and Marita K. Cardinal of Western Oregon University. The study was supported by OSU.

For the study, researchers reviewed U.S. medical schools’ websites, looking for all physical activity-related coursework. They reviewed both public and private schools, and schools of medicine and osteopathic medicine. In all, 118 of the 170 accredited schools had curriculum information available online.

Of those, 51 percent offered no physical activity related coursework, and 21 percent offered only one course. And 82 percent of the schools reviewed did not require students to take any physical activity-related courses.

Schools may be spending more time on the topic than appears in the published curriculum, but the absence of physical activity in those documents suggests exercise education is not formalized or institutionalized to the degree it ought to be, given its role in helping people stay healthy, Cardinal said.

“I’m an outsider looking in, and I was expecting to see more than what we did,” he said.

Lifestyle-related chronic illnesses such as heart disease and diabetes are among the leading causes of death and disability, and one of the most important ways to prevent such chronic diseases is through regular physical activity participation, he said.

Physicians play a significant and influential role in encouraging and assisting patients who need or are trying to get more exercise, but past research has shown that many physicians lack the education, skills or confidence to educate and counsel patients about their physical activity, Cardinal said.

“Understanding why and how to exercise, and knowing how to help people who are struggling to make it a habit, is really important,” he said.

This issue is gaining more attention nationally.The American College of Sports Medicine supports an “Exercise is Medicine” initiative, designed to encourage primary care physicians and other health care providers to include physical activity in the treatment plans of their patients.

Exercise is also a key component of the U.S. government’s “Healthy People 2020” initiative to improve health across the nation, and the National Physical Activity Plan to increase physical activity for all Americans, Cardinal said.

If medical schools do not include physical activity education in their curriculums, physicians or other health care workers may need to find other ways to educate themselves about exercise and its role in keeping people healthy, or perhaps give the nod to other professionals who can, Cardinal said.

“We really need to see something happen to address this,” he said. “How do we get it more institutionalized into medical school curriculum? This is a question researchers have been asking for 40 years now. It is about time we figured it out.”

via Exercise largely absent from US medical school curriculum, study shows — ScienceDaily.

Dr. Court’s Comments:

While I am sure exercise is emphasized to some degree in all medical curricula, it is disturbing to know that the most effective treatment (along with diet) for chronic disease prevention is not formally taught to the students who will eventually be entrusted with keeping people from getting sick. Combine this with the information that almost no nutrition is taught in medical school either, I think we may have found why our medical system is so broken. Research is very clear that disease is far easier to prevent than it is to treat once it’s developed. Prevention is with diet and exercise. My experience in practice has taught me that most medical doctors are terribly ill-equipped to recommend the right kind of diet or exercise to their patients. Some of the information being given to patients is flat out wrong. They often recommend things that make patients more likely, not less, to develop chronic disease. A scary thought, indeed.